Augusto Vitale, dell'Istituto Superiore di Sanità, presenta la cosiddetta regola delle 3R, come forma mentis per la ricerca scientifica:
- Replacement, sostituzione della sperimentazione animale con metodi alternativi.- Reduction, riduzione del numero di animali.- Refinement, miglioramento delle condizioni degli animali.
Il principio delle 3R è stato proposto nel 1959 da W.M.S. Russell e R.L. Burch per ridurre l'impatto della sperimentazione sugli animali.
Sperimentazione animale e principio delle 3R
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Discovered a New Carbon-Carbon Chemical Bond

A group of researchers from Hokkaido University has provided the first experimental evidence of the existence of a new type of chemical bond: the single-electron covalent bond, theorized by Linus Pauling in 1931 but never verified until now. Using derivatives of hexaarylethane (HPE), the scientists were able to stabilize this unusual bond between two carbon atoms and study it with spectroscopic techniques and X-ray diffraction. This discovery opens new perspectives in understanding bond chemistry and could lead to the development of new materials with innovative applications.
In the cover image: study of the sigma bond with X-ray diffraction. Credits: Yusuke Ishigaki
After nearly a year of review, on September 25, a study was published in Nature that has sparked a lot of discussion, especially among chemists. A group of researchers from Hokkaido University synthesized a molecule that experimentally demonstrated the existence of a new type of chemical bond, something that does not happen very often.